Class I and IIB HDAC inhibitor 42
CAS No. 2245323-24-2
Class I and IIB HDAC inhibitor 42 ( —— )
产品货号. M13603 CAS No. 2245323-24-2
Class I and IIB HDAC inhibitor 42 is a novel potent, selective class I and IIB inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Class I and IIB HDAC inhibitor 42
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Class I and IIB HDAC inhibitor 42 is a novel potent, selective class I and IIB inhibitor.
-
产品描述Class I and IIB HDAC inhibitor 42 is a novel potent, selective class I and IIB inhibitor (HDAC1 Ki=0.27 nM) for topical treatment of cutaneous t-cell lymphoma.
-
同义词——
-
通路Cell Cycle/DNA Damage
-
靶点HDAC
-
受体HDAC
-
研究领域——
-
适应症——
化学信息
-
CAS Number2245323-24-2
-
分子量413.40
-
分子式C19H22F3N3O4
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCC(C)(CCCCC(=O)NO)NC1=C(C(=O)C1=O)NC2=CC=C(C=C2)C(F)(F)F
-
化学全称6-((3,4-dioxo-2-((4-(trifluoromethyl)phenyl)amino)cyclobut-1-en-1-yl)amino)-N-hydroxy-6-methylheptanamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Fournier JF, et al. Bioorg Med Chem Lett. 2018 Sep 15;28(17):2985-2992.
产品手册
关联产品
-
OBP-801
OBP-801 (YM 753;Spiruchostatin A) is a novel cyclic-peptide-based HDAC inhibitor with IC50 of 2 nM.
-
Mocetinostat
An isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15 uM).
-
ACY-738
ACY-738 (ACY738) is a potent and specific HDAC6 inhibitor (IC50=1.7 nM) with improved brain bioavailability; displays 60-1500 fold selectivity over class I HDACs.